ABSTRACT
A hematopoese extramedular (HEM) é um mecanismo fisiológico compensatório de produção de células sanguíneas fora da medula óssea motivada por uma produção inadequada dessas células. Os locais mais comuns da HEM são o fígado, o baço e as regiões paraespinhais do tórax, mas pode acometer praticamente qualquer órgão ou tecido e simular lesões neoplásicas. No presente artigo relatamos o caso de um paciente atendido na emergência por um trauma de baixo impacto que, ao exame tomográfico, apresentava hepatoesplenomegalia e massas abdominais consideradas compatíveis com focos de hematopoese extramedular em correlação com dados clínicos do paciente de mielofibrose
Extramedullary hematopoiesis is a compensatory physiological mechanism of production of blood cells outside the bone marrow motivated by inadequate production of these cells. The most common sites are the liver, spleen and paraspinal regions of the chest but can affect virtually any organ or tissue and simulate neoplastic lesions. In the present article we report the case of a patient treated in the emergency room with a low impact trauma who presented on computed tomography hepatosplenomegaly and abdominal masses considered compatible with foci of extramedullary hematopoiesis in correlation with clinical data of myelofibrosis
ABSTRACT
Hemangiomas são tumores vasculares benignos raros na mama. São de origem extraparenquimal e desenvolvem-se no tecido celular subcutâneo. O diagnóstico por exames de imagem pode ser difícil já que não apresentam características específicas, podendo ser confundidos com tumores malignos. Relatamos nesse artigo o caso de uma paciente portadora de hemangioma mamário em que a mamografia de rastreamento inicialmente demonstrou resultado inconclusivo, havendo necessidade de complementação diagnóstica com exame clínico e ultrassonografia para o laudo final de achados benignos (BI-RADS 2)
Hemangiomas are rare benign vascular tumors in the breast. They have extra parenchymal developing in the subcutaneous cellular tissue. Diagnosis by imaging exams can be difficult since this type of benign tumor does not have specific characteristics and can be confused with malignant tumors. We report in this article the case of a patient with breast hemangioma on screening mammography who initially had inconclusive result requiring clinical examination and ultrasound for the final report of benign findings (BI-RADS 2)
ABSTRACT
ABSTRACT BACKGROUND: Thyroid autoimmunity is more common in patients with rheumatic diseases than in healthy populations. The degree of association seems subject to influence from patients' geographical location. Here, we aimed to ascertain the prevalence of thyroid autoantibodies in a cohort of patients with systemic rheumatic disease and the degree of association between its presence and inflammatory activity. DESIGN AND SETTING: Cross-sectional observational study in a rheumatology unit. METHODS: 301 patients with systemic lupus erythematosus (SLE), 210 with rheumatoid arthritis (RA), 58 with scleroderma (SSc) and 80 with spondyloarthritis (SpA) were studied regarding thyroid function (TSH and T4), anti-thyroglobulin (TgAb) and anti-thyroperoxidase (TPOab) and compared with 141 healthy controls. Disease activity in patients with rheumatic disease was assessed through appropriate indexes. RESULTS: There were more antithyroid antibodies in SLE patients with hypothyroidism (P = 0.01; odds ratio, OR 2.7; 95% confidence interval, CI: 1.20-6.26) and in those without hypothyroidism (P = 0.06; OR 2.4; 95% CI: 1.28-4.55) than in controls. SSc patients also showed: P = 0.03 both with antithyroid antibodies and hypothyroidism (OR 3.4; 95% CI: 1.06-10.80) and without hypothyroidism (OR 3.1; 95% CI: 1.11-0.13). RA and SpA patients had the same prevalence as controls (P not significant). Presence of autoantibodies with and without hypothyroidism was not associated with the activity or functional indexes evaluated. CONCLUSION: SLE and SSc were associated with higher prevalence of thyroid autoantibodies in patients with and without hypothyroidism, unlike SpA and RA. There was no link between thyroid autoantibody presence and disease activity or functional impairment.